Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011669)
Formula
SVG example
Reduction
Reactant Nestorone Product 5alpha-dihydrosegesterone acetate
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Reduction - Reduction
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011673 Nestorone 17alpha-deacetylsegesterone acetate Oxidation - Deacetylation Nestorone [1]
MR011670 Nestorone 20alpha?-dihydrosegesterone acetate Reduction - Reduction Nestorone [1]
MR011671 Nestorone 3alpha, 5alpha-tetrahydrosegesterone acetate Reduction - Reduction Nestorone [1]
MR011672 Nestorone 3beta, 5alpha-tetrahydrosegesterone acetate Reduction - Reduction Nestorone [1]
MR011674 Nestorone 4, 5-dihydro-17alpha-deacetylsegesterone acetate Oxidation - Deacetylation Nestorone [1]
References
1 Nestorone? as a Novel Progestin for Nonoral Contraception: Structure-Activity Relationships and Brain Metabolism Studies

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