Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011741)
Formula
SVG example
Unclear
Reactant INX-09054 Product INX-09122
Reactant Info Product Info
Metabolic Enzyme Adenosine 5'-monophosphoramidase (HINT1) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011740 INX-189 INX-09054 Unclear - Unclear INX-189 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011742 INX-09122 INX-09175 Unclear - Unclear INX-189 [1]
References
1 In Vitro Metabolite Formation in Human Hepatocytes and Cardiomyocytes and Metabolism and Tissue Distribution in Monkeys of the 2'-C-Methylguanosine Prodrug BMS-986094 : Potential Role in Clinical Cardiovascular Toxicity

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