Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011885)
Formula Reactant KRP-297 Metabolite M25 Product KRP-297 Metabolite M1
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Dimethylaniline oxidase 3 (FMO3) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011884 KRP-297 Metabolite M2 KRP-297 Metabolite M25 Unclear - Unclear KRP-297 [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011886 KRP-297 Metabolite M25 KRP-297 Metabolite M15 Unclear - Unclear KRP-297 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011888 KRP-297 Metabolite M1 KRP-297 Metabolite M20 Unclear - Unclear KRP-297 [1]
MR011887 KRP-297 Metabolite M1 KRP-297 Metabolite M5,M9 Unclear - Unclear KRP-297 [1]
References
1 Absorption, metabolism, and excretion of [14C]MK-0767 (2-methoxy-5-(2,4-dioxo-5-thiazolidinyl)-N-[[4-(trifluoromethyl)phenyl] methyl]benzamide) in humans

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