Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012011)
Formula Reactant M409-3 Product M379
Reactant Info Product Info
Metabolic Type Oxidation - Mono-oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012010 Fruquintinib M409-3 Oxidation - Mono-oxidation fruquintinib [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012012 M379 M365-2/3 Unclear - Unclear fruquintinib [2]
References
1 A phase I study to investigate the metabolism, excretion, and pharmacokinetics of [(14)C]fruquintinib, a novel oral selective VEGFR inhibitor, in healthy Chinese male volunteers
2 Efficacy and safety of taxane monotherapy in advanced gastric cancer refractory to triplet chemotherapy with docetaxel, cisplatin, and S-1: a multicenter retrospective study

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