General Information of This Metabolic Reaction (MR) (ID: MR012010)
Formula
SVG example
Mono-oxidation
Reactant Fruquintinib Product M409-3
Reactant Info Product Info
Metabolic Type Oxidation - Mono-oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012030 Fruquintinib M205 Unclear - Unclear fruquintinib [1]
MR012015 Fruquintinib M379-1 Unclear - Unclear fruquintinib [2], [3]
MR012019 Fruquintinib M379-2 Oxidation - O-desmethylation fruquintinib [4]
MR012028 Fruquintinib M380 Unclear - Unclear fruquintinib [5]
MR012034 Fruquintinib M409-1 Unclear - Unclear fruquintinib [6], [3]
MR012023 Fruquintinib M409-2 Oxidation - Mono-oxidation fruquintinib [7], [3]
MR012033 Fruquintinib M409-4 Oxidation - Mono-oxidation fruquintinib [8], [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012011 M409-3 M379 Oxidation - Mono-oxidation fruquintinib [9]
References
1 Locus coeruleus neuronal activity correlates with behavioral response to acute and chronic doses of methylphenidate (Ritalin) in adolescent rats
2 Incarceration of the medial collateral ligament in the intercondylar notch following proximal avulsion
3 Preclinical pharmacokinetics and disposition of a novel selective VEGFR inhibitor fruquintinib (HMPL-013) and the prediction of its human pharmacokinetics
4 Internal resources among informal caregivers: trajectories and associations with well-being
5 Spontaneous thrombosis of a giant cerebral varix in a pediatric patient
6 Esophageal bezoar due to karaya gum granules used as a laxative
7 A simple and rapid infrared-assisted self enzymolysis extraction method for total flavonoid aglycones extraction from Scutellariae Radix and mechanism exploration
8 Management of postoperative junctional ectopic tachycardia in pediatric patients: a survey of 30 centers in Germany, Austria, and Switzerland
9 Electrolyte disorders with platinum-based chemotherapy: mechanisms, manifestations and management

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