Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012024)
Formula
SVG example
Unclear
Reactant M409-2 Product M425-2
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012023 Fruquintinib M409-2 Oxidation - Mono-oxidation fruquintinib [1], [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012026 M409-2 M395-1 Unclear - Unclear fruquintinib [3]
MR012027 M409-2 M585 Unclear - Unclear fruquintinib [4]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012025 M425-2 M395-2 Unclear - Unclear fruquintinib [5]
References
1 A simple and rapid infrared-assisted self enzymolysis extraction method for total flavonoid aglycones extraction from Scutellariae Radix and mechanism exploration
2 Preclinical pharmacokinetics and disposition of a novel selective VEGFR inhibitor fruquintinib (HMPL-013) and the prediction of its human pharmacokinetics
3 Hydrophilic interaction liquid chromatography-tandem mass spectrometry for quantitation of paralytic shellfish toxins: validation and application to reference materials
4 Derivatization-free LC-MS/MS method for estrogen quantification in mouse brain highlights a local metabolic regulation after oral versus subcutaneous administration
5 Aptamer-based fluorescence-quenching lateral flow strip for rapid detection of mercury (II) ion in water samples

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