Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012109)
Formula
CYP2D6 ...
SVG example
Unclear
Reactant Omecamtiv mecarbil Product Omecamtiv mecarbil Metabolites M3
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2D6 (CYP2D6) DME Info
Lauric acid omega-hydroxylase (CYP4A11) DME Info
Cytochrome P450 4F2 (CYP4F2) DME Info
Leukotriene B4 omega-hydroxylase (CYP4F3) DME Info
Cytochrome P450 4F12 (CYP4F12) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012116 Omecamtiv mecarbil Omecamtiv mecarbil Metabolites M1 Unclear - Unclear Omecamtiv mecarbil [1]
MR012114 Omecamtiv mecarbil Omecamtiv mecarbil Metabolites M14 Unclear - Unclear Omecamtiv mecarbil [1]
MR012117 Omecamtiv mecarbil Omecamtiv mecarbil Metabolites M2 Unclear - Unclear Omecamtiv mecarbil [1]
MR012118 Omecamtiv mecarbil Omecamtiv mecarbil Metabolites M21 Unclear - Unclear Omecamtiv mecarbil [1]
MR012106 Omecamtiv mecarbil Omecamtiv mecarbil Metabolites M5 Unclear - Unclear Omecamtiv mecarbil [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012112 Omecamtiv mecarbil Metabolites M3 Omecamtiv mecarbil Metabolites M39 Unclear - Unclear Omecamtiv mecarbil [1]
MR012110 Omecamtiv mecarbil Metabolites M3 Omecamtiv mecarbil Metabolites M4 Unclear - Unclear Omecamtiv mecarbil [1]
References
1 Pharmacokinetics, Disposition, and Biotransformation of [(14)C]Omecamtiv Mecarbil in Healthy Male Subjects after a Single Intravenous or Oral Dose

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