Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012428)
Formula Reactant AZD8931 M12 Product AZD8931 M17
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012427 AZD8931 AZD8931 M12 Oxidation - O-desmethylation AZD8931 [1]
References
1 Metabolic disposition of AZD8931, an oral equipotent inhibitor of EGFR, HER2 and HER3 signalling, in rat, dog and man

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