Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012437)
Formula Reactant AZD8931 M10 Product AZD8931 M4
Reactant Info Product Info
Metabolic Type Oxidation - Monooxygenation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012436 AZD8931 AZD8931 M10 Other reaction - Hydroxy-chlorofluorophenylation AZD8931 [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012438 AZD8931 M10 AZD8931 M3,M6,M7 Conjugation - Monooxygenated glucosidation AZD8931 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012435 AZD8931 M11 AZD8931 M4 Oxidation - Monooxygenation AZD8931 [1]
MR012433 AZD8931 M9 AZD8931 M4 Unclear - Unclear AZD8931 [1]
References
1 Metabolic disposition of AZD8931, an oral equipotent inhibitor of EGFR, HER2 and HER3 signalling, in rat, dog and man

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