Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012493)
Formula
SVG example
Hydroxylation
Reactant YM-758 Product Precursor
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012495 YM-758 YM-394111 Oxidation - O-demethylation YM-758 [1]
MR012496 YM-758 YM-394112 Oxidation - O-demethylation YM-758 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012494 Precursor AS2036313-00 Other reaction - Deprotonation YM-758 [1]
References
1 Evaluation of the inhibitory and induction potential of YM758, a novel If channel inhibitor, for human P450-mediated metabolism

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