Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012602)
Formula	Reactant	LMP400 Metabolite M3	Product	LMP400 Metabolite M4
Formula	Reactant	Reactant Info	Product	Product Info
Metabolic Type	Conjugation - Alkylation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR012601	LMP400	LMP400 Metabolite M3	Oxidation - Demethylenation	LMP400	[1]

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR012603	LMP400 Metabolite M3	LMP400 Metabolite M5	Conjugation - Alkylation	LMP400	[1]

References
1	Identification, synthesis, and biological evaluation of metabolites of the experimental cancer treatment drugs indotecan (LMP400) and indimitecan (LMP776) and investigation of isomerically hydroxylated indenoisoquinoline analogues as topoisomerase I poisons

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