General Information of This Metabolic Reaction (MR) (ID: MR012602)
Formula Reactant LMP400 Metabolite M3 Product LMP400 Metabolite M4
Reactant Info Product Info
Metabolic Type Conjugation - Alkylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012601 LMP400 LMP400 Metabolite M3 Oxidation - Demethylenation LMP400 [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012603 LMP400 Metabolite M3 LMP400 Metabolite M5 Conjugation - Alkylation LMP400 [1]
References
1 Identification, synthesis, and biological evaluation of metabolites of the experimental cancer treatment drugs indotecan (LMP400) and indimitecan (LMP776) and investigation of isomerically hydroxylated indenoisoquinoline analogues as topoisomerase I poisons

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