Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012656)
Formula Reactant BMS-275183 Product BMS-275183 Metabolite M23
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012650 BMS-275183 Unclear Unclear - Unclear BMS-275183 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012657 BMS-275183 Metabolite M23 BMS-275183 Metabolite M20 Unclear - Unclear BMS-275183 [1]
MR012658 BMS-275183 Metabolite M23 BMS-275183 Metabolite M20B Unclear - Unclear BMS-275183 [1]
References
1 CYP3A4-mediated ester cleavage as the major metabolic pathway of the oral taxane 3'-tert-butyl-3'-N-tert-butyloxycarbonyl-4-deacetyl-3'-dephenyl-3'-N-debenzoyl-4-O-methoxycarbonyl-paclitaxel (BMS-275183)

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