Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012685)
Formula Reactant Opened-ring metabolite (M2) Product M2-glutathione conjugate (M0)
Reactant Info Product Info
Metabolic Type Conjugation - Glutathione conjugation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012682 MGI-114 Opened-ring metabolite (M2) Unclear - Unclear MGI-114 [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012684 Opened-ring metabolite (M2) M2-glucuronide conjugate (M'2) Conjugation - Glucuronidation MGI-114 [1]
MR012683 Opened-ring metabolite (M2) M2-glutathione conjugate (M'1) Conjugation - Glutathione conjugation MGI-114 [1]
References
1 Pharmacokinetics, metabolism, and routes of excretion of intravenous irofulven in patients with advanced solid tumors

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