Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012702)
Formula
SVG example
Glucuronidation
Reactant N2-hydroxy-PhIP Product N2-hydroxy-PhIP-N2-glucuronide metabolite
Reactant Info Product Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012698 PhIP 4'-hydroxy-PhIP Oxidation - Hydroxylation PhIP [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012699 4'-hydroxy-PhIP 4'-Hydroxy-PhIP-O-Sulfate metabolite Conjugation - Sulfation PhIP [1]
MR012700 N2-hydroxy-PhIP N2-acetoxy-PhIP Conjugation - Acetylation PhIP [1]
MR012703 N2-hydroxy-PhIP N2-hydroxy-PhIP-N3-glucuronide metabolite Conjugation - Glucuronidation PhIP [1]
MR012701 N2-hydroxy-PhIP N2-sulfonyloxy-PhIP Conjugation - Sulfation PhIP [1]
References
1 Differential metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in mice humanized for CYP1A1 and CYP1A2

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