Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012729)
Formula Reactant Hydroxyurea Product Carbamoyl nitroso
Reactant Info Product Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012732 Hydroxyurea Acetohydroxamic acid Other reaction - Breakdown Hydroxyurea [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012730 Carbamoyl nitroso Nitroxyl (HNO) Hydrolysis - Hydrolysis Hydroxyurea [2]
MR012731 Carbamoyl nitroso NO Unclear - Unclear Hydroxyurea [2]
References
1 American Society of Health-System Pharmacists 2015; Drug Information 2015. Bethesda, MD. 2015, p. 1065
2 Hydroxyurea (therapeutics and mechanism): metabolism, carbamoyl nitroso, nitroxyl, radicals, cell signaling and clinical applications

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