Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013042)
Formula	Unclear
	Reactant	Darexaban N-oxides	Product	Darexaban maleate Metabolite M2
	Reactant	Reactant Info	Product	Product Info
Metabolic Type	Unclear - Unclear

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR013041	Darexaban maleate	Darexaban N-oxides	Unclear - Unclear	Darexaban maleate	[1]

Other MR(s) Related to The Product of This MR

Other MR(s) That Produce The Product of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR013044	Darexaban glucuronide	Darexaban maleate Metabolite M2	Unclear - Unclear	Darexaban maleate	[2]

References
1	Identification of enzymes responsible for the N-oxidation of darexaban glucuronide, the pharmacologically active metabolite of darexaban, and the glucuronidation of darexaban N-oxides in human liver microsomes
2	Absorption, metabolism and excretion of darexaban (YM150), a new direct factor Xa inhibitor in humans

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