Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013042)
Formula
SVG example
Unclear
Reactant Darexaban N-oxides Product Darexaban maleate Metabolite M2
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013041 Darexaban maleate Darexaban N-oxides Unclear - Unclear Darexaban maleate [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013044 Darexaban glucuronide Darexaban maleate Metabolite M2 Unclear - Unclear Darexaban maleate [2]
References
1 Identification of enzymes responsible for the N-oxidation of darexaban glucuronide, the pharmacologically active metabolite of darexaban, and the glucuronidation of darexaban N-oxides in human liver microsomes
2 Absorption, metabolism and excretion of darexaban (YM150), a new direct factor Xa inhibitor in humans

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