Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013041)
Formula
SVG example
Unclear
Reactant Darexaban maleate Product Darexaban N-oxides
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013043 Darexaban maleate Darexaban glucuronide Unclear - Unclear Darexaban maleate [1], [2]
MR013039 Darexaban maleate Darexaban maleate Metabolite M5 Unclear - Unclear Darexaban maleate [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013042 Darexaban N-oxides Darexaban maleate Metabolite M2 Unclear - Unclear Darexaban maleate [1]
References
1 Absorption, metabolism and excretion of darexaban (YM150), a new direct factor Xa inhibitor in humans
2 Identification of UDP-glucuronosyltransferases responsible for the glucuronidation of darexaban, an oral factor Xa inhibitor, in human liver and intestine

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