Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR013094)
Formula	Unclear
	Reactant	Mono-N-desethylamiodarone		Product	Di-N-desethylamiodarone
	Reactant	Reactant Info		Product	Product Info
Metabolic Type	Unclear - Unclear

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR013093	Amiodarone hydrochloride	Mono-N-desethylamiodarone	Oxidation - N-dealkylation	Amiodarone hydrochloride	[1], [2], [3]

References
1	Determination of the cardiac drug amiodarone and its N-desethyl metabolite in sludge samples
2	Amiodarone and concurrent antiretroviral therapy: a case report and review of the literature
3	The metabolism of amiodarone by various CYP isoenzymes of human and rat, and the inhibitory influence of ketoconazole. J Pharm Pharm Sci. 2008;11(1):147-59.

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