Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013115)
Formula
SVG example
Unclear
Reactant Meperidine Product Meperidinic acid
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013117 Meperidine Meperidine N-oxide Oxidation - N-demethylation Meperidine [1]
MR013118 Meperidine Methoxy-hydroxymeperidine Unclear - Unclear Meperidine [1]
MR013111 Meperidine Normeperidine Oxidation - N-demethylation Meperidine [2], [3], [4]
MR013119 Meperidine p-hydrox ymeperidine Unclear - Unclear Meperidine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013116 Meperidinic acid Normeperidinic acid Hydrolysis - Hydrolysis Meperidine [1]
References
1 Urinary excretion of meperidine and its metabolites
2 Meperidine and normeperidine levels following meperidine administration during labor. I. Mother
3 Effects of ethinyl estradiol on pharmacokinetics of meperidine and pentobarbital in the rat
4 Impact of cytochrome P450 variation on meperidine N-demethylation to the neurotoxic metabolite normeperidine. Xenobiotica. 2020 Feb;50(2):209-222.

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