Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013150)
Formula Reactant Pexacerfont Product Pexacerfont Metabolite M8
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013153 Pexacerfont BMS-749241 Unclear - Unclear Pexacerfont [1]
MR013148 Pexacerfont DPH-123554 Unclear - Unclear Pexacerfont [1]
MR013146 Pexacerfont DPH-124921 Unclear - Unclear Pexacerfont [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013151 Pexacerfont Metabolite M8 Pexacerfont Metabolite M2 Unclear - Unclear Pexacerfont [1]
MR013152 Pexacerfont Metabolite M8 Pexacerfont Metabolite M3 Unclear Pexacerfont [1]
References
1 In vitro and in vivo metabolism and pharmacokinetics of BMS-562086, a potent and orally bioavailable corticotropin-releasing factor-1 receptor antagonist

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