Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013199)
Formula Reactant Ponesimod M12 Metabolite (ACT-204426) Product Ponesimod M13 Metabolite (ACT-338275)
Reactant Info Product Info
Metabolic Type Multi-steps Reaction - Hydrolysis; oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013198 Ponesimod Ponesimod M12 Metabolite (ACT-204426) Oxidation - Oxidationn Ponesimod [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013202 Ponesimod M12 Metabolite (ACT-204426) Ponesimod M32 Metabolite Oxidation - Dealkylation Ponesimod [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013200 Ponesimod M13 Metabolite (ACT-338275) Ponesimod M32 Metabolite Oxidation - Dealkylation Ponesimod [1]
References
1 Mass balance, pharmacokinetics and metabolism of the selective S1P1 receptor modulator ponesimod in humans

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