Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013279)
Formula
NAT1 ...
SVG example
Reactant Zafirlukast metabolite M1 Product Zafirlukast metabolite M2
Reactant Info Product Info
Metabolic Enzyme N-acetyltransferase 1 (NAT1) DME Info
N-acetyltransferase 2 (NAT2) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013278 Zafirlukast Zafirlukast metabolite M1 Hydrolysis - Hydrolysis Zafirlukast [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013280 Zafirlukast metabolite M2 Zafirlukast metabolite M4 Oxidation - Methyl-hydroxylation Zafirlukast [1], [2]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
2 Metabolism and excretion of zafirlukast in dogs, rats, and mice

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