Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013280)
Formula	Methyl-hydroxylation
	Reactant	Zafirlukast metabolite M2	Product	Zafirlukast metabolite M4
	Reactant	Reactant Info	Product	Product Info
Metabolic Type	Oxidation - Methyl-hydroxylation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR013279	Zafirlukast metabolite M1	Zafirlukast metabolite M2	Unclear	Zafirlukast	[1], [2]

Other MR(s) Related to The Product of This MR

Other MR(s) That Metabolize The Produtc of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR013281	Zafirlukast metabolite M4	Zafirlukast metabolite M3	Unclear	Zafirlukast	[1], [2]

References
1	Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
2	Metabolism and excretion of zafirlukast in dogs, rats, and mice

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