Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013540)
Formula Reactant Sotorasib Metabolite M24 Product Sotorasib Metabolite M6
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013539 Sotorasib Sotorasib Metabolite M24 Oxidation - Oxidation Sotorasib [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013541 Sotorasib Metabolite M6 Sotorasib Metabolite M37 Unclear Sotorasib [1]
References
1 Absorption, Distribution, Metabolism, and Excretion of [(14)C]-Sotorasib in Rats and Dogs: Interspecies Differences in Absorption, Protein Conjugation and Metabolism
2 Absorption, metabolism and excretion of [(14)C]-sotorasib in healthy male subjects: characterization of metabolites and a minor albumin-sotorasib conjugate

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