Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013613)
Formula	CYP1A2
	Reactant	NITD609 Metabolite M18	Product	NITD609 Metabolite M23
	Reactant	Reactant Info	Product	Product Info
Metabolic Enzyme	Cytochrome P450 1A2 (CYP1A2)				DME Info

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR013611	NITD609 Metabolite M37	NITD609 Metabolite M18	Unclear	NITD609	[1]

Other MR(s) Related to The Product of This MR

Other MR(s) That Metabolize The Produtc of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR013614	NITD609 Metabolite M23	NITD609 Metabolite M16	Unclear	NITD609	[1]
MR013615	NITD609 Metabolite M23	NITD609 Metabolite M21.8,M23.5A	Unclear	NITD609	[1]

References
1	KAE609 (Cipargamin), a New Spiroindolone Agent for the Treatment of Malaria: Evaluation of the Absorption, Distribution, Metabolism, and Excretion of a Single Oral 300-mg Dose of [14C]KAE609 in Healthy Male Subjects

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