Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013809)
Formula
CYP
SVG example
Unclear
Reactant Methimazole Product Methimazole M6
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 (CYP) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013815 Methimazole Methimazole M13 Unclear - Unclear Methimazole [1]
MR013817 Methimazole N-methylthiourea Unclear - Unclear Methimazole [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013810 Methimazole M6 Methimazole M7 Unclear - Unclear Methimazole [1]
References
1 Evidence for the involvement of N-methylthiourea, a ring cleavage metabolite, in the hepatotoxicity of methimazole in glutathione-depleted mice: structure-toxicity and metabolic studies
2 Role of CYP2A6 in Methimazole Bioactivation and Hepatotoxicity

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