Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013817)
Formula
SVG example
Unclear
Reactant Methimazole Product N-methylthiourea
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2A6 (CYP2A6) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013815 Methimazole Methimazole M13 Unclear - Unclear Methimazole [1]
MR013809 Methimazole Methimazole M6 Unclear - Unclear Methimazole [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013811 Methimazole M7 Methimazole M5b Unclear - Unclear Methimazole [1]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013812 Methimazole M5b Methimazole M9 Unclear - Unclear Methimazole [1]
References
1 Evidence for the involvement of N-methylthiourea, a ring cleavage metabolite, in the hepatotoxicity of methimazole in glutathione-depleted mice: structure-toxicity and metabolic studies

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