Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013857)
Formula
SVG example
Unclear
Reactant Almonertinib Product Almonertinib Metabolite HS-10296-M2
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A (CYP3A) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013863 Almonertinib Almonertinib Metabolite M511a Unclear - Unclear Almonertinib [1]
MR013875 Almonertinib Almonertinib Metabolite M511b Unclear - Unclear Almonertinib [1]
MR013873 Almonertinib Almonertinib Metabolite M541a and M541c Unclear - Unclear Almonertinib [1]
MR013870 Almonertinib Almonertinib Metabolite M646 Unclear - Unclear Almonertinib [1]
MR013878 Almonertinib Almonertinib Metabolite M717 Unclear - Unclear Almonertinib [1]
MR013877 Almonertinib HS-10296-M30 Unclear - Unclear Almonertinib [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013859 Almonertinib Metabolite HS-10296-M2 Almonertinib Metabolite M440 Unclear - Unclear Almonertinib [1]
MR013860 Almonertinib Metabolite HS-10296-M2 Almonertinib Metabolite M470a,M470b,M470c,M470d Unclear - Unclear Almonertinib [1]
MR013861 Almonertinib Metabolite HS-10296-M2 Almonertinib Metabolite M470e Unclear - Unclear Almonertinib [1]
MR013858 Almonertinib Metabolite HS-10296-M2 Almonertinib Metabolite M575 Unclear - Unclear Almonertinib [1]
References
1 Absorption, metabolism, excretion, and safety of [(14)C]almonertinib in healthy Chinese subjects

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