| General Information of This Metabolic Reaction (MR) (ID:
MR013893) |
| Formula |
|
| Reactant |
Sinomenine |
Product |
N-demethyl-sinomenine |
|
Reactant Info
|
Product Info
|
|
Metabolic Enzyme
|
Cytochrome P450 3A4 (CYP3A4)
|
DME Info
|
|
Mephenytoin 4-hydroxylase (CYP2C19)
|
DME Info
|
|
Metabolic Type
|
Unclear
-
Unclear
|
|
|
|
|
|
|
|
| Other MR(s) Related to The Reactant of This MR |
|
Other MR(s) That Metabolize The Reactant of This MR
|
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| References |
| 1 |
Metabolic mechanism and anti-inflammation effects of sinomenine and its major metabolites N-demethylsinomenine and sinomenine-N-oxide
|
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