Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR014024)
Formula Reactant RP101075 Product RP112289
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005573 Ozanimod RP101075 Oxidation - N-Dealkylation Ozanimod [1]
MR005566 RP101988 RP101075 Unclear Ozanimod [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR014019 RP101075 CC112273 Unclear Ozanimod [2]
MR014021 RP101075 RP101442 Unclear Ozanimod [1]
MR005567 RP101075 CC112273 Unclear Ozanimod [2]
MR005569 RP101075 RP101442 Unclear Ozanimod [1]
References
1 Absorption, Metabolism, and Excretion, In Vitro Pharmacology, and Clinical Pharmacokinetics of Ozanimod, a Novel Sphingosine 1-Phosphate Receptor Modulator
2 DrugBank(Pharmacology-Metabolism):Ozanimod

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