General Information of Xenobiotics (ID: XEO00199)
Xenobiotics Name
Doxycycline
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
54671203
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [1]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [1]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [1]
DME(s) Induced by This Xenobiotics
UDP-glucuronosyltransferase 1A10 (UGT1A10) DME Info Homo sapiens [2]
UDP-glucuronosyltransferase 1A8 (UGT1A8) DME Info Homo sapiens [2]
References
1 Doxycycline interferes with quorum sensing-mediated virulence factors and biofilm formation in gram-negative bacteria. World J Microbiol Biotechnol. 2013 Jun;29(6):949-57.
2 Aryl hydrocarbon receptor protects lung adenocarcinoma cells against cigarette sidestream smoke particulates-induced oxidative stress. Toxicol Appl Pharmacol. 2012 Mar 15;259(3):293-301.

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