Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00393)
Xenobiotics Name
Dehydroepiandrosterone
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=5881"></iframe>
3D MOL 2D MOL
PubChem CID
5881
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Steroid 17-alpha-monooxygenase (CYP17A1) DME Info Homo sapiens [1]
Aromatase (CYP19A1) DME Info Homo sapiens [2]
Cytochrome P450 1A2 (CYP1A2) DME Info Homo sapiens [3]
References
1 Inhibition of CYP17 expression by adrenal androgens and transforming growth factor beta in adrenocortical cells. Acta Biochim Pol. 2004;51(4):907-17.
2 Conversion of dehydroepiandrosterone to downstream steroid hormones in macrophages. J Endocrinol. 2000 Feb;164(2):161-9.
3 Dehydroepiandrosterone post-transcriptionally modifies CYP1A2 induction involving androgen receptor. Chem Biol Interact. 2013 May 25;203(3):597-603.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.