General Information of Xenobiotics (ID: XEO00396)
Xenobiotics Name
Gentamicin
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
3467
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [1]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [1]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [1]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [1]
DME(s) Induced by This Xenobiotics
Alpha-L-iduronidase (IDUA) DME Info Homo sapiens [2]
References
1 Lysozyme associated liposomal gentamicin inhibits bacterial biofilm. Int J Mol Sci. 2017 Apr 9;18(4).
2 Gentamicin-mediated suppression of Hurler syndrome stop mutations restores a low level of alpha-L-iduronidase activity and reduces lysosomal glycosaminoglycan accumulation. Hum Mol Genet. 2001 Feb 1;10(3):291-9.

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