Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00545)
Xenobiotics Name
Lucanthone
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Drug in Phase 2 Clinical Trial
Structure
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3D MOL 2D MOL
PubChem CID
10180
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Asparagine synthetase (ASNS) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Cytochrome P450 1A1 (CYP1A1) DME Info Homo sapiens [2]
Methylsterol monooxygenase 1 (MSMO1) DME Info Homo sapiens [3], [4]
References
1 Drug interaction study of flavonoids toward CYP3A4 and their quantitative structure activity relationship (QSAR) analysis for predicting potential effects. Toxicol Lett. 2018 Sep 15;294:27-36.
2 Induction of differentiation of myeloid leukemia cells in primary culture in response to lithocholic acid acetate, a bile acid derivative, and cooperative effects with another differentiation inducer, cotylenin A. Leuk Res. 2008 Jul;32(7):1112-23.
3 In vitro detection of drug-induced phospholipidosis using gene expression and fluorescent phospholipid based methodologies. Toxicol Sci. 2007 Sep;99(1):162-73.
4 A toxicogenomic approach to drug-induced phospholipidosis: analysis of its induction mechanism and establishment of a novel in vitro screening system. Toxicol Sci. 2005 Feb;83(2):282-92.

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