Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00767)
Xenobiotics Name
Ciglitazone
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Investigative Agent
Structure
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3D MOL 2D MOL
PubChem CID
2750
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Carboxylesterase 1 (CES1) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Fatty acid desaturase 1 (FADS1) DME Info Homo sapiens [2]
Proline dehydrogenase 1 (PRODH) DME Info Homo sapiens [3]
Prostaglandin G/H synthase 2 (COX-2) DME Info Homo sapiens [4]
References
1 Cloning of the human cholesteryl ester hydrolase promoter: identification of functional peroxisomal proliferator-activated receptor responsive elements. Biochem Biophys Res Commun. 2001 Jun 22;284(4):1065-70.
2 Delta5 desaturase mRNA levels are increased by simvastatin via SREBP-1 at early stages, not via PPARalpha, in THP-1 cells. Eur J Pharmacol. 2007 Oct 1;571(2-3):97-105.
3 Apoptotic action of peroxisome proliferator-activated receptor-gamma activation in human non small-cell lung cancer is mediated via proline oxidase-induced reactive oxygen species formation. Mol Pharmacol. 2007 Sep;72(3):674-85.
4 Cyclooxygenase-2 expression by nonsteroidal anti-inflammatory drugs in human airway smooth muscle cells: role of peroxisome proliferator-activated receptors. J Immunol. 2003 Jan 15;170(2):1043-51.

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