General Information of Xenobiotics (ID: XEO00816)
Xenobiotics Name
Aflatoxin M1
Xenobiotics Type
Health or Environmental Toxicant(s)
Classification
Carcinogen
Structure
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3D MOL 2D MOL
PubChem CID
15558498
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Cytosolic branched aminotransferase (BCAT1) DME Info Homo sapiens [1]
Dihydrofolate reductase (DHFR) DME Info Homo sapiens [1]
UDP-glucuronosyltransferase 2B15 (UGT2B15) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Cytochrome P450 1A1 (CYP1A1) DME Info Homo sapiens [1]
Cytochrome P450 3A4 (CYP3A4) DME Info Homo sapiens [2]
References
1 Transcriptome analysis revealed that aflatoxin M1 could cause cell cycle arrest in differentiated Caco-2 cells. Toxicol In Vitro. 2019 Sep;59:35-43.
2 Aflatoxins upregulate CYP3A4 mRNA expression in a process that involves the PXR transcription factor. Toxicol Lett. 2011 Aug 28;205(2):146-53.

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