Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00872)
Xenobiotics Name
Acetaldehyde
Xenobiotics Type
Health or Environmental Toxicant(s)
Classification
Health Hazard/Toxicant
Structure
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3D MOL 2D MOL
PubChem CID
177
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Acetylcholinesterase (ACHE) DME Info Homo sapiens [1]
Catalase (CAT) DME Info Homo sapiens [2]
S-adenosylmethionine synthase 2 (MAT2A) DME Info Homo sapiens [3]
DME(s) Induced by This Xenobiotics
Nitric oxide synthase inducible (NOS2) DME Info Homo sapiens [4]
Prostaglandin G/H synthase 1 (COX-1) DME Info Homo sapiens [5]
Prostaglandin G/H synthase 2 (COX-2) DME Info Homo sapiens [3]
Xanthine dehydrogenase/oxidase (XDH) DME Info Homo sapiens [4]
References
1 Slow-binding inhibition of carboxylesterase and other serine hydrolases by chlorodifluoroacetaldehyde. Chem Res Toxicol. 1993 Sep-Oct;6(5):630-4.
2 Cytokine response and oxidative stress produced by ethanol, acetaldehyde and endotoxin treatment in HepG2 cells. Isr Med Assoc J. 2001 Feb;3(2):131-6.
3 In vitro effects of aldehydes present in tobacco smoke on gene expression in human lung alveolar epithelial cells. Toxicol In Vitro. 2013 Apr;27(3):1072-81.
4 Mechanism of alcohol-induced oxidative stress and neuronal injury. Free Radic Biol Med. 2008 Dec 1;45(11):1542-50.
5 mRNA induction and cytokine release of inflammatory mediators during in vitro exposure of human nasal respiratory epithelia to acetaldehyde. Inhal Toxicol. 2006 Dec;18(14):1083-90.

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