General Information of Xenobiotics (ID: XEO01286)
Xenobiotics Name
Egtazic acid
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Investigative Agent
Structure
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3D MOL 2D MOL
PubChem CID
6207
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [1]
Nitric oxide synthase brain (NOS1) DME Info Homo sapiens [2]
Nitric oxide synthase endothelial (NOS3) DME Info Homo sapiens [3]
Serum paraoxonase/arylesterase 1 (PON1) DME Info Homo sapiens [4]
References
1 Inhibition by EGTA of the formation of a biofilm by clinical strains of Staphylococcus aureus. J Basic Microbiol. 2014 Jul;54(7):700-10.
2 Involvement of the nitric oxide/protein kinase G pathway in polychlorinated biphenyl-induced cell death in SH-SY 5Y neuroblastoma cells. J Neurosci Res. 2006 Aug 15;84(3):692-7.
3 Calcium-dependent nitric oxide production is involved in the cytoprotective properties of n-acetylcysteine in glycochenodeoxycholic acid-induced cell death in hepatocytes. Toxicol Appl Pharmacol. 2010 Jan 15;242(2):165-72.
4 Esterase detoxication of acetylcholinesterase inhibitors using human liver samples in vitro. Toxicology. 2016 Apr 15;353-354:11-20.

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