Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO01320)
Xenobiotics Name
Glyphosate
Xenobiotics Type
Health or Environmental Toxicant(s)
Classification
Environmental Pollutant
Structure
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3D MOL 2D MOL
PubChem CID
3496
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Aromatase (CYP19A1) DME Info Homo sapiens [1], [2]
Cytochrome P450 2C9 (CYP2C9) DME Info Homo sapiens [3]
Superoxide dismutase 1 (SOD1) DME Info Homo sapiens [4]
DME(s) Induced by This Xenobiotics
Catalase (CAT) DME Info Homo sapiens [5]
References
1 Differential effects of glyphosate and roundup on human placental cells and aromatase. Environ Health Perspect. 2005 Jun;113(6):716-20.
2 Time- and dose-dependent effects of roundup on human embryonic and placental cells. Arch Environ Contam Toxicol. 2007 Jul;53(1):126-33.
3 An evaluation of the cytochrome P450 inhibition potential of selected pesticides in human hepatic microsomes. J Environ Sci Health B. 2009 Aug;44(6):553-63.
4 Emptying of intracellular calcium pool and oxidative stress imbalance are associated with the glyphosate-induced proliferation in human skin keratinocytes HaCaT cells. ISRN Dermatol. 2013 Aug 29;2013:825180.
5 Influence of the spray adjuvant on the toxicity effects of a glyphosate formulation. Toxicol In Vitro. 2014 Oct;28(7):1306-11.

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