Detail Information of Xenobiotics
| General Information of Xenobiotics (ID: XEO01324) | ||||||
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| Xenobiotics Name |
GSK-J4
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| Xenobiotics Type |
Pharmaceutical Agent(s)
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| Classification |
Preclinical/Patented Drug
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| Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=71729975"></iframe>
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| 3D MOL | 2D MOL | |||||
| PubChem CID | ||||||
| DME(s) Modulated by This Xenobiotics | ||||||
| DME(s) Inhibited by This Xenobiotics | ||||||
| Hydroxyacid-oxoacid transhydrogenase (ADHFE1) | DME Info | Homo sapiens | [1] | |||
| Aldo-keto reductase 1C3 (AKR1C3) | DME Info | Homo sapiens | [1] | |||
| Adenine phosphoribosyltransferase (APRT) | DME Info | Homo sapiens | [1] | |||
| Arylsulfatase A (ARSA) | DME Info | Homo sapiens | [1] | |||
| NADPH-dependent carbonyl reductase 1 (CBR1) | DME Info | Homo sapiens | [1] | |||
| Carboxylesterase 2 (CES2) | DME Info | Homo sapiens | [1] | |||
| Vitamin D 25-hydroxylase (CYP2R1) | DME Info | Homo sapiens | [1] | |||
| Delta(24)-sterol reductase (DHCR24) | DME Info | Homo sapiens | [1] | |||
| Dihydrofolate reductase (DHFR) | DME Info | Homo sapiens | [1] | |||
| Fatty acid desaturase 1 (FADS1) | DME Info | Homo sapiens | [1] | |||
| Fatty acid desaturase 2 (FADS2) | DME Info | Homo sapiens | [1] | |||
| Folylpolyglutamate synthase (FPGS) | DME Info | Homo sapiens | [1] | |||
| Friedreich ataxia protein (FXN) | DME Info | Homo sapiens | [1] | |||
| Methionine-R-sulfoxide reductase B2 (MSRB2) | DME Info | Homo sapiens | [1] | |||
| Methylenetetrahydrofolate reductase (MTHFR) | DME Info | Homo sapiens | [1] | |||
| Alpha-N-acetylglucosaminidase (NAG) | DME Info | Homo sapiens | [1] | |||
| Phosphoribosylformylglycinamidine synthase (PFAS) | DME Info | Homo sapiens | [1] | |||
| Purine nucleoside phosphorylase (PNP) | DME Info | Homo sapiens | [1] | |||
| Thymidine phosphorylase (TYMP) | DME Info | Homo sapiens | [1] | |||
| Thymidylate synthase (TYMS) | DME Info | Homo sapiens | [1] | |||
| Uridine 5'-monophosphate synthase (UMPS) | DME Info | Homo sapiens | [1] | |||
| DME(s) Induced by This Xenobiotics | ||||||
| Dicarbonyl/L-xylulose reductase (DCXR) | DME Info | Homo sapiens | [1] | |||
| Metallothionein-2A (MT2A) | DME Info | Homo sapiens | [1] | |||
| References | ||||||
| 1 | Inhibition of histone H3K27 demethylases selectively modulates inflammatory phenotypes of natural killer cells. J Biol Chem. 2018 Feb 16;293(7):2422-2437. | |||||
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