General Information of Xenobiotics (ID: XEO01419)
Xenobiotics Name
Oxyquinoline
Xenobiotics Type
Health or Environmental Toxicant(s)
Classification
Acute Toxic Substance
Structure
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3D MOL 2D MOL
PubChem CID
1923
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Alcohol dehydrogenase class-II (ADH4) DME Info Homo sapiens [1]
Beta-lactamase (blaB) DME Info Serratia marcescens [2]
HMG-CoA reductase (HMGCR) DME Info Homo sapiens [3]
Methylsterol monooxygenase 1 (MSMO1) DME Info Homo sapiens [4]
Arylamine N-acetyltransferase (NAT) DME Info Serratia marcescens [2]
References
1 Oxadiazon affects the expression and activity of aldehyde dehydrogenase and acylphosphatase in human striatal precursor cells: A possible role in neurotoxicity. Toxicology. 2019 Jan 1;411:110-121.
2 Long-chain 4-aminoquinolines as quorum sensing inhibitors in Serratia marcescens and Pseudomonas aeruginosa. ACS Chem Biol. 2017 May 19;12(5):1425-1434.
3 Effect of curcumin on cisplatin- and oxaliplatin-induced oxidative stress in human embryonic kidney (HEK) 293 cells. Ren Fail. 2011;33(5):518-23.
4 Down-regulation of thymidylate synthase expression and its steady-state mRNA by oxaliplatin in colon cancer cells. Anticancer Drugs. 2004 Apr;15(4):371-6.

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