Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO01507)
Xenobiotics Name
Lead nitrate
Xenobiotics Type
Health or Environmental Toxicant(s)
Classification
Health Hazard/Toxicant
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=24924"></iframe>
3D MOL 2D MOL
PubChem CID
24924
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Porphobilinogen synthase (ALAD) DME Info Homo sapiens [1]
Cytochrome P450 1A2 (CYP1A2) DME Info Homo sapiens [2]
DME(s) Induced by This Xenobiotics
Cytosolic phospholipase A2 (PLA2G4A) DME Info Homo sapiens [3]
Prostaglandin G/H synthase 2 (COX-2) DME Info Homo sapiens [4], [5]
References
1 A comparison of the effects of inorganic and alkyllead compounds on human erythrocytic delta-aminolevulinic acid dehydratase (ALAD) activity in vitro. J Appl Toxicol. 1991 Apr;11(2):103-10.
2 Effect of metals on polycyclic aromatic hydrocarbon induction of CYP1A1 and CYP1A2 in human hepatocyte cultures. Toxicol Appl Pharmacol. 2001 Jan 15;170(2):93-103.
3 Involvement of the epidermal growth factor receptor in Pb+-induced activation of cPLA?COX-2 genes and PGE?production in vascular smooth muscle cells. Toxicology. 2011 Jan 11;279(1-3):45-53.
4 Divalent lead cations induce cyclooxygenase-2 gene expression by epidermal growth factor receptor/nuclear factor-kappa B signaling in A431carcinoma cells. Toxicol Lett. 2011 Jun 10;203(2):147-53.
5 Function of DNA methyltransferase 3a in lead (Pb(2+) )-Induced Cyclooxygenase-2 gene. Environ Toxicol. 2015 Sep;30(9):1024-32.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.