General Information of Xenobiotics (ID: XEO01551)
Xenobiotics Name
Heliotrine
Xenobiotics Type
Natural Product(s), Extract(s) or Medicine(s)
Classification
Natural Product
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=906426"></iframe>
3D MOL 2D MOL
PubChem CID
906426
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Succinate-semialdehyde dehydrogenase (ALDH5A1) DME Info Homo sapiens [1]
Aminomuconic semialdehyde dehydrogenase (ALDH12) DME Info Homo sapiens [1]
Cytochrome P450 3A5 (CYP3A5) DME Info Homo sapiens [1]
Cytochrome P450 3A7 (CYP3A7) DME Info Homo sapiens [1]
Lauric acid omega-hydroxylase (CYP4A11) DME Info Homo sapiens [1]
Leukotriene B4 omega-hydroxylase (CYP4F3) DME Info Homo sapiens [1]
Dihydrothymine dehydrogenase (DPYD) DME Info Homo sapiens [1]
Bifunctional epoxide hydrolase 2 (EPHX2) DME Info Homo sapiens [1]
Dimethylaniline oxidase 3 (FMO3) DME Info Homo sapiens [1]
Histamine N-methyltransferase (HNMT) DME Info Homo sapiens [1]
Monoamine oxidase type A (MAO-A) DME Info Homo sapiens [1]
Monoamine oxidase type B (MAO-B) DME Info Homo sapiens [1]
Sulfotransferase 1E1 (SULT1E1) DME Info Homo sapiens [1]
Sulfotransferase 2A1 (SULT2A1) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
L-glutamine amidohydrolase (GLS) DME Info Homo sapiens [1]
References
1 Disturbance of gene expression in primary human hepatocytes by hepatotoxic pyrrolizidine alkaloids: A whole genome transcriptome analysis. Toxicol In Vitro. 2015 Oct;29(7):1669-82.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.