Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO01553)
Xenobiotics Name
Isoflavone
Xenobiotics Type
Natural Product(s), Extract(s) or Medicine(s)
Classification
Natural Product
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=72304"></iframe>
3D MOL 2D MOL
PubChem CID
72304
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Cytochrome P450 1A1 (CYP1A1) DME Info Homo sapiens [1]
Dihydrofolate reductase (DHFR) DME Info Homo sapiens [2]
Monoamine oxidase type A (MAO-A) DME Info Homo sapiens [2]
DME(s) Induced by This Xenobiotics
Fatty acid desaturase 2 (FADS2) DME Info Homo sapiens [2]
Quinone reductase 1 (NQO1) DME Info Homo sapiens [2], [3]
Thioredoxin reductase TR1 (TXNRD1) DME Info Homo sapiens [2]
References
1 Novel 2-amino-isoflavones exhibit aryl hydrocarbon receptor agonist or antagonist activity in a species/cell-specific context. Toxicology. 2012 Jul 16;297(1-3):26-33.
2 Soy isoflavones exert differential effects on androgen responsive genes in LNCaP human prostate cancer cells. J Nutr. 2007 Apr;137(4):964-72.
3 Soy isoflavones alter expression of genes associated with cancer progression, including interleukin-8, in androgen-independent PC-3 human prostate cancer cells. J Nutr. 2006 Jan;136(1):75-82.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.