Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO01554)
Xenobiotics Name
Isoimperatorin
Xenobiotics Type
Natural Product(s), Extract(s) or Medicine(s)
Classification
Natural Product
Structure
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3D MOL 2D MOL
PubChem CID
68081
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Cytochrome P450 1B1 (CYP1B1) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Glutathione S-transferase alpha-2 (GSTA2) DME Info Homo sapiens [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Cytochrome P450 1B1 (CYP1B1) DME Info Ki = 6 microM [1]
References
1 Inhibitors of cytochrome P450 (CYP) 1B1. Eur J Med Chem. 2017 Jul 28;135:296-306.
2 Potent protective effect of isoimperatorin against aflatoxin B1-inducible cytotoxicity in H4IIE cells: bifunctional effects on glutathione S-transferase and CYP1A. Carcinogenesis. 2006 Dec;27(12):2483-90.

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