General Information of Xenobiotics (ID: XEO01597)
Xenobiotics Name
Carbofuran
Xenobiotics Type
Fungicide(s), Herbicide(s) or Insecticide(s)
Classification
Pesticide/Insecticide
Structure
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3D MOL 2D MOL
PubChem CID
2566
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Acetylcholinesterase (ACHE) DME Info Homo sapiens [1]
Butyrylcholine esterase (BCHE) DME Info Homo sapiens [2]
DME(s) Induced by This Xenobiotics
Cytochrome P450 2B6 (CYP2B6) DME Info Homo sapiens [3]
Cytochrome P450 3A4 (CYP3A4) DME Info Homo sapiens [3]
References
1 3-Oxoisoxazole-2(3H)-carboxamides and isoxazol-3-yl carbamates: Resistance-breaking acetylcholinesterase inhibitors targeting the malaria mosquito, Anopheles gambiae. Bioorg Med Chem. 2015 Mar 15;23(6):1321-40.
2 Malathion, carbofuran and paraquat inhibit Bungarus sindanus (krait) venom acetylcholinesterase and human serum butyrylcholinesterase in vitro. Ecotoxicology. 2007 May;16(4):363-9.
3 Characterization of human cytochrome P450 induction by pesticides. Toxicology. 2012 Mar 29;294(1):17-26.

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