General Information of Xenobiotics (ID: XEO02930)
Xenobiotics Name
Indolicidin derivative CP10A
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Azoreductase (azoR) DME Info Enterococcus faecalis [1]
Azoreductase (azoR) DME Info Streptococcus pyogenes [1]
Unclear metabolic mechanism (DME-unclear) DME Info Enterococcus faecalis [1]
Glutamate decarboxylase (gadB) DME Info Listeria monocytogenes [1]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [1]
Tyrosine decarboxylase (tdc) DME Info Enterococcus faecalis [1]
VanA ligase (vanA) DME Info Enterococcus faecalis [1]
VanB ligase (vanB) DME Info Enterococcus faecalis [1]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Azoreductase (azoR) DME Info MIC = 8 ug/ml [1]
Azoreductase (azoR) DME Info MIC = 1 ug/ml [1]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 8 ug/ml [1]
Glutamate decarboxylase (gadB) DME Info MIC = 1 ug/ml [1]
NADPH-dependent oxidoreductase (nfrA) DME Info MIC = 4 ug/ml [1]
Tyrosine decarboxylase (tdc) DME Info MIC = 8 ug/ml [1]
VanA ligase (vanA) DME Info MIC = 8 ug/ml [1]
VanB ligase (vanB) DME Info MIC = 8 ug/ml [1]
References
1 Structure and mechanism of action of an indolicidin peptide derivative with improved activity against gram-positive bacteria. J Biol Chem. 2001 Jun 29;276(26):24015-22.

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