General Information of Xenobiotics (ID: XEO04560)
Xenobiotics Name
Phlebotomus duboscqi defensin
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Cytochrome P450 monooxygenase 51A (cyp51A) DME Info Aspergillus fumigatus [1]
Unclear metabolic mechanism (DME-unclear) DME Info Saccharomyces cerevisiae [1]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [1]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Cytochrome P450 monooxygenase 51A (cyp51A) DME Info MIC = 12.5-25 microM [1]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 25-50 microM [1]
NADPH-dependent oxidoreductase (nfrA) DME Info MIC = 0.78-1.56 microM [1]
References
1 Characterization of a defensin from the sand fly Phlebotomus duboscqi induced by challenge with bacteria or the protozoan parasite Leishmania major. Infect Immun. 2004 Dec;72(12):7140-6.

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