General Information of Xenobiotics (ID: XEO05098)
Xenobiotics Name
Temporin-PEa
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Azoreductase (azoR) DME Info Enterococcus faecalis [1]
Unclear metabolic mechanism (DME-unclear) DME Info Enterococcus faecalis [1]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [1]
Tyrosine decarboxylase (tdc) DME Info Enterococcus faecalis [1]
VanA ligase (vanA) DME Info Enterococcus faecalis [1]
VanB ligase (vanB) DME Info Enterococcus faecalis [1]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Azoreductase (azoR) DME Info MIC = 2.0 microM [1]
Unclear metabolic mechanism (DME-unclear) DME Info MIC = 2.0 microM [1]
NADPH-dependent oxidoreductase (nfrA) DME Info MIC = 1.0 microM [1]
Tyrosine decarboxylase (tdc) DME Info MIC = 2.0 microM [1]
VanA ligase (vanA) DME Info MIC = 2.0 microM [1]
VanB ligase (vanB) DME Info MIC = 2.0 microM [1]
References
1 Identification and target-modifications of temporin-PE: a novel antimicrobial peptide in the defensive skin secretions of the edible frog, Pelophylax klesculentus. Biochem Biophys Res Commun. 2018 Jan 22;495(4):2539-2546.

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