Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO05156)
Xenobiotics Name
Tobramycin
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
36294
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Ampc beta-lactamase (ampC) DME Info Burkholderia cenocepacia [1]
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [1]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [1]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [2]
Beta-lactamase (blaB) DME Info Burkholderia cenocepacia [1]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [1]
References
1 The quorum sensing inhibitor hamamelitannin increases antibiotic susceptibility of Staphylococcus aureus biofilms by affecting peptidoglycan biosynthesis and eDNA release. Sci Rep. 2016 Feb 1;6:20321.
2 Antibacterial and anti-biofilm effects of cathelicidin peptides against pathogens isolated from cystic fibrosis patients. Peptides. 2011 Sep;32(9):1807-14.

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